MyBioSource.com's RABBIT ANTI HUMAN INTERLEUKIN-31 is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, and Western Blot. The RABBIT ANTI HUMAN INTERLEUKIN-31 Antibody was generated using IL-31, IL31, and Interleukin 31 as the antigen and it reacts with Human.
Description
Rabbit anti Human Interleukin-31 antibody recognizes human IL-31 (interleukin-31), a 141 amino acid T-cell derived cytokine and member of the IL-6 cytokine family, which shares homology with oncostatin M, cardiotrophin-1 and LIF (leukaemia inhibitory factor). IL-31 is preferentially produced by type 2 helper T cells (Th2) and signals through binding to the IL-31 receptor consisting of IL-31 receptor A (IL-31RA/GPL) and oncostatin M receptor B, activators of STAT1, STAT3 and STAT5. IL-31 is an important mediator of T cell mediated immune response and is particularly linked with diseases of the skin, including dermatitis and pruritic atopic skin inflammation, and is also implicated in bronchial inflammation